[HTML][HTML] Development and characterization of a recombinant infectious bronchitis virus expressing the ectodomain region of S1 gene of H120 strain
YQ Wei, HC Guo, H Dong, HM Wang, J Xu… - Applied microbiology …, 2014 - Springer
Infectious bronchitis (IB), caused by infectious bronchitis virus (IBV), is a highly contagious
chicken disease, and can lead to serious economic losses in poultry enterprises. The
continual introduction of new IBV serotypes requires alternative strategies for the production
of timely and safe vaccines against the emergence of variants. Modification of the IBV
genome using reverse genetics is one way to generate recombinant IBVs as the candidates
of new IBV vaccines. In this study, the recombinant IBV is developed by replacing the …
chicken disease, and can lead to serious economic losses in poultry enterprises. The
continual introduction of new IBV serotypes requires alternative strategies for the production
of timely and safe vaccines against the emergence of variants. Modification of the IBV
genome using reverse genetics is one way to generate recombinant IBVs as the candidates
of new IBV vaccines. In this study, the recombinant IBV is developed by replacing the …
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